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「カイ栓菌に関する文献情報」(医学研究者用)

カイ栓菌は、学名【Trametes robiniophila Murr.】です。

カイ栓菌菌糸体エキスによる製品は中華人民共和国国家食品薬品監督管理局(State Food and Drug Administration, SFDA)に登録されています。(登録番号Z-20000109)

カイ栓菌については、中国のみならず、米国等でも多数の研究論文が発表されています。

英字論文についての一般表記はHuaier, jinkeですが、Huaierは中国語の発音で、Jinkeは中国国家食品薬品監督管理局に登録しているカイ栓菌菌糸体エキスによる製品の商標登録の英文です。


Effect of Huaier granule on recurrence after curative resection of HCC: a multicentre, randomised clinical trial (世界初1044人の肝臓がん患者臨床試験の論文)
Gutjnl-2018;0:1-11.doi:10.1136/gutjnl-2018-315983(2017Impact Factor:16.658

Huaier extract synergizes with tamoxifen to induce autophagy and apoptosis in ER-positive breast cancer cells(TAMとカイ栓菌投与による乳がん細胞のアポトーシスについて)
DOI: 10.18632/oncotarget.8303 March 23, 2016

腫瘍以外の分野でのカイ栓菌の応用
日本補完代替医療学会誌 第11巻 第1号 (2014年3月)

Protective effects of Huang Qi Huai granules on adriamycin nephrosis in rats  
Pediatr Nephrol (2011) 26:905?913

Inhibitory Effect of Extract of Fungi of Huaier on Hepatocellular Carcinoma Cells 
J Huazhong Univ Sci Technol[Med Sci]

Apoptosis-inducing effect of Jinke on Molt-4 cells and its mechanism*
Chinese-German Journal of Clinical Oncology August 2008, Vol. 7, No. 8, P487?P491

Anticancer Effect of PS-T on the Experimental Hepatocellular Carcinoma
The Chinese-German Journal of Clinical Oncology Mar. 2004, Vol.3, No.1 P55?P59

Effects of Huaier aqueous extract on proliferation and apoptosis in the melanomacell line A875
ONCOLOGY LETTERS 5: 1171-1176, 2013 Received October 13, 2012; Accepted January 4, 2013

A polysaccharide from the fungi of Huaier exhibits anti-tumor potential and immunomodulatory effects
Carbohydrate Polymers 92 (2013) 577? 582

Huaier Aqueous Extract Inhibits Ovarian Cancer Cell Motility via the AKT/GSK3b/b-Catenin Pathway
PLOS ONE | 14 May 2013 | Volume 8 | Issue 5 | e63731

Huaier aqueous extract suppresses human breast cancer cell proliferation through inhibition of estrogen receptor α signaling
INTERNATIONAL JOURNAL OF ONCOLOGY July 2013 Volume 43 Number 1

Huaier aqueous extract inhibits proliferation of breast cancer cells by inducing apoptosis
Cancer Sci | 2010 | 9 Japanese Cancer Association

Huaier aqueous extract suppresses human breast cancer cell proliferation through inhibition of estrogen receptor α signaling
INTERNATIONAL JOURNAL OF ONCOLOGY

Role of Huaier Extract as a Promising Anticancer Drug
Adaptive Medicine 4(2): 2012

Huai Qi Huang ameliorates proteinuria and hematuria in mild IgA nephropathy patients:A prospective randomized controlled study
Journal of the Formosan Medical Association (2013) 112, 766e772

The anticancer effect of Huaier(カイ栓菌の抗がん作用)
ONCOLOGY REPORTS (2013) Received December 11, 2014; Accepted March 24, 2015

Huaier aqueous extract induces apoptosis of human fibrosarcoma HT1080 cells through the mitochondrial pathway(カイ栓菌の肉腫論文)
ONCOLOGY LETTERS 9: 1590-1596, 2015  Received April 9, 2014; Accepted January 8, 2015

Anti-angiogenic and antitumor activities of Huaier aqueous extract(カイ栓菌の抗血管形成)
ONCOLOGY REPORTS 28: 1167-1175, 2012 Received June 12, 2012; Accepted July 13, 2012

Huaier Cream Protects against Adriamycin-Induced Nephropathy by Restoring Mitochondrial Function via PGC-1α Upregulation(カイ栓菌の腎症の保護)
Hindawi Publishing Corporation PPAR Research Volume 2015, Article ID 720383, 11 pages http://dx.doi.org/10.1155/2015/720383

Huaier Extract Induces Autophagic Cell Death by Inhibiting the mTOR/S6K Pathway in Breast Cancer Cells 
PLOS ONE | DOI:10.1371/journal.pone.0131771 July 2, 2015

The anticancer effect of Huaier (Review)(カイ栓菌の抗がん作用)
ONCOLOGY REPORTS Received December 11, 2014; Accepted March 24, 2015 DOI: 10.3892/or.2015.3950

Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway(カイ栓菌の肝臓がん細胞論文)
Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Article ID 171356

Preliminary study of Huai Qi Huang granules delay the development of primary glomerular diseases in human(腎不全カイ栓菌の臨床)
2014 Informa Healthcare USA, Inc. DOI: 10.3109/0886022X.2014.952746

「Effect of Huaier granule on recurrence after curative resection of HCC: a multicentre, randomised clinical trial」(カイ栓菌を使用した肝臓がん治療における臨床事例)